Stem Cell-based Tolerance Induction in Transplantation
نویسندگان
چکیده
منابع مشابه
Stem Cell-based Tolerance Induction in Transplantation
The use of stem cell-based protocols in transplantation has rapidly achieved many long-sought goals, including the induction of donor-specific tolerance and as an effective immunomodulatory therapy against acute cellular rejection and graft-versus-host disease. Recent advances in the fields of transplant immunology and regenerative medicine have significantly improved outcomes after solid organ...
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There is great interest worldwide in discovering and developing a permanent source of tissues which would be capable of generating any cell type and which would avoid the problem of transplant rejection. Stem cells are cells that can specialize into the many different cells found in the human body. The ethical objections concerning stem cells have focused primarily on their source. Human embry...
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The introduction and evolution of hematopoietic stem cell transplantation (HSCT) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. Today, HSCT is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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Background Stem cell transplantation has become as a novel treatment for end-stage kidney, lung, heart , liver diseases and several hematologic disorders. Improved survival of transplant recipients has raised awareness of post-transplant complications. One of these complications is transplant-related osteoporosis. Methods In this manuscript we review prevention methods for transplant-relat...
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Hematopoietic stem/progenitor cells (HSPCs) which give rise to different blood cell types are present within the bone marrow microenvironment, especially in flat bones such as skull, vertebrae, pelvis and chest. Interacting factors such as stromal derived factor-1/CXCR4, very late antigen-4/vascular cell adhesion molecule-1, Lymphocyte function-associated antigen-1/ intercellular adhesion molec...
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ژورنال
عنوان ژورنال: Journal of Stem Cell Research & Therapy
سال: 2013
ISSN: 2157-7633
DOI: 10.4172/2157-7633.s6-003